Looking for macOS app that can remap the two thumb buttons on a mouse to simulate a combination of keystrokes. This software should be compatible with macOS Ventura and can be paid for.

The software should prevent the button click from registering with the active window. Instead, it should cause that click to be ignored and simulate the keyboard keystrokes as a replacement.

Would also be great if different rules could be set up with different applications.

Example setup using X-Button Mouse on Windows:

X-Button Mouse example on Winodws

1 Answer 1


I think SteerMouse should be able to do all you need.

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There's also USB Overdrive though I've never used that one myself.

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