Several web-browsers are getting better at allowing visually impaired to change settings (i.e. increasing font and resizing frames based on responsive design), but for e-mail clients there seems to be less focus. The solution is often to use windows magnifiers, which quickly makes it confusing for the user to navigate. Increasing standard zoom in Windows messes up navigation, as the e-mail reader windows cannot cope with the zooming.
I have tried out the Windows e-mail-reader and the Apple e-mail-reader as well as Gmails without success. Do you know of any e-mail reader working on Windows 10 that allows for dramatically larger font (i.e. 36ish) without messing up the navigation?