Is there open source software that a hospital's IRB can run which permits electronic submission and ongoing management? For it to be useful it needs to have an active (or at least more active than dormant) developer community and user community.
Open source software has a more communicative and more capable user base than proprietary software. The online help I have seen for open source software is the best I have seen. Furthermore, data is generally stored in non-proprietary formats that make it easier to move to a different platform or to query.