I hate to answer my own question, but here are the results of my research. I won't accept this as an answer for a while in case someone does recommend a proper replacement that fulfils my requirements.
The following list is largely based on this wikipedia-article, but also other lists I found online. I only tested those browsers that offered compiled Windows-versions for download and weren't older than QtWeb. My tests included using google.com, youtube and tubeplus.is. The latter was used to test the efficiency of the ad-blockers. It uses different flash based videostreaming services and sometimes serves some nasty popups/popunders that can't be closed.
Browzar 2.0.0.0
Size: 222KB
Portable style: single executable
experience:
based on IE rendering engine
no video playback on youtube
doesn't even render its developer's website correctly
long freezes between page clicks that trigger Window's "application is not responding dialog" after every single click
froze and crashed when quitting the program
conclusion: unusable
Midori
Size: 160MB
Portable style: dumps user settings into Windows user directory instead of own folder, 1500+ files, 300+ subfolders, portable needs to be started via bat hidden in subdirectory
experience:
conclusion: unusable
K-Meleon 75.1
Size: 65MB
Portable style: 350+ files, 100+ subfolders, keeps user files in own directory
experience:
youtube works, but warned that the browser was outdated
built in ready to go ad-blocker, but with a tiny rule set. During the adblock test a popup was loaded that refused to close and played an audio message over and over so that I needed to close the entire browser forcefully through task manager just to get rid of it. Session was saved though, but that also included the horrible ad.
quick website rendering
conclusion: usable, but the adblocker's filter list is not compatible with that of adblock plus and thus would require a lot of effort to fine tune and keep up to date
Liri 0.3
Size: 130MB
Portable style: dumps user settings into Windows user directory instead of own folder, 1300+ files, 68 subfolders
experience: no adblocker or plugin support, page rendering ok
conclusion: useless due to total lack of security features
Qupzilla 1.8.9
Size: 91MB
Portable style: dumps user settings into Windows user directory instead of own folder, 360+ files, 48 folders
experience:
quick and correct page rendering
built in adblocker with adblock plus compatible list support
allows to set location for cache directory (in own folder by default), but the location of the user files
Conclusion: usable, but not truly portable
SlimJet 8.0.5.0
Size: 230Mb
Portable style: keeps user files in own folder, but creates temp files in outside own folder, 800+ files, 120 folders
Experience:
- built-in ABP-compatible adblocker
- quick and proper page rendering
Conclusion: perfect if it wasn't for the fact that it's bigger than Firefox and thus everything but lightweight
Palemoon 26.1.1 x86
Size: 48 MB
Portable style: 270+files, 50 folders, keeps all user files in own directory, but makes use of Windows temp folder
Experience:
Firefox-derivative that's optimized for size and efficiency
supports all Firefox plugins and thus proper adblockers
proper and fast page rendering without errors
Conclusion: usable
Opera Portable USB 12.18
Size: 51 MB
Portable Style: 570+ files, 80+ folders, keeps user files in own folder
Experience:
comes with rudimentary adblocker, but also supports ABP via plugin
proper but sluggish page rendering
unintuitive menus
Conclusion: usable
SlimBrowser 7.00
Size: 12MB
Portable Style: 450+ files, 40+ folders, seems to keep user files in own folder
Experience: started with error message that rendered all controls unusable. No webpage could be accessed
Conclusion: unusable
Superbird 44
Size: 150MB
Portable Style: 200 files, 8 folders, keeps user data in own folder
Experience:
Conclusion: usable
NetGroove 1.0
Size: 440 KB
Portable Style: single executable
Experience: requires NetFramework 3.5, couldn't be tested
Conclusion: useless on systems without necessary NetFramework version
Dooble 1.55
Size: 108MB
Portable Style: 440+ files, 50 folders, keeps user data in own folder
Experience:
fast rendering, but neither Youtube nor flash video playback works
seemingly no built in adblocker, but not all ads were displayed which is probably the result of the lacking flash support
- supposedly supports plugins, but the menu option does nothing
Conclusion: very limited browser
Avant Browser 12.5
Size: 470MB
Portable Style: 1200+ files, 500+ folders, keeps user data in own folder
Experience:
- built in rudimentary adblocker which in its default state doesn't work too great
built in popup blocker that didn't seem to work at all
sluggish page rendering performance
seemingly no plugin support
confusing browser behavior: New tab automatically loads prior tab's link. Try opening a new one to hide the fact you've been watching porn. Also, waste of bandwidth for people on metered connections.
horribly unintuitive interface
Conclusion: bloatware
Comodo IceDragon
Size: 180MB
Portable Style: 1000+ files, 50+ folders, keeps user files in own folder, but also makes use of Windows temp folder
Experience:
- Firefox based --> plugin and therefor adblock support
- fast and proper page rendering
- is not offered as downloadable archive. Portable version has to be installed via installer.
Conclusion: usable
Final conclusion
There doesn't seem to be a single browser out there that could be a complete alternative to QtWeb regarding size, resource usage, feature richness and portability without having to trade off one aspect for another.
After all those tests, the next best alternative to it seems to be Palemoon, but I'm still holding my breath for a suggestion of an obscure browser that might surprise me.