I know that such soft as BitDefenter or Kaspersky will not work under VirtualBox. I know also that there are some specific kinds of antiviruses designed specifically for work under virtual enviroments, but I'm interested in regular antiviruses. What alternative to VirtualBox would you offer ?
I personally avoid an open-source software like VirtualBox because exactlly that "liberty" of code is what makes it a bad choice for specific requisites like this.
I recommend you privative VMWare products, you can choose between VMWare Player or VMWare WorkStation. Player is a liimited but free version of Workstation.
I tested Kaspersky and MalwareBytes products without problems in VMWare VirtualMachines with various Windows installed.