The easiest and most portable solution would be to create your interactive presentation as a mini-web site, with local relative links, images and possibly sounds. Then simply put the whole minisite on the USB drives. If there is a file called index.html in the root directory of the drive a lot of computers will automatically open it.
You can have automatic transitions between pages based on time, transitions based on clicking links, images, parts of images the lot.
- Should work on any computer that has a web browser, (check it for working on multiple browsers).
- Cross Platform
- No software to install
- Unlikely to trigger virus alerts
- Very flexible
- Can include links to the company website or other resources
- Familiar user interface
There are lots of web page creators out there but you can use LibreOffice Impress to make a presentation and export it as a html document.